PLoS One, published by the Public Library of Science, was launched in 2006. Last year, it became the largest scientific journal in the world, publishing nearly 7,000 articles. Foir impact, it is now ranked 12th in biology journals, not bad going for a journal less than 5 years old. PLoS One's success has led other players in the field think about launching open access journals. Does the success of this kind of multi-disciplinary, open access, journal signal the demise of the specialised, highly-selective subscription journal? Read more here.