Streptococcus - the key link between gum disease and heart disease
New research from the UK may have discovered an explanation for
the link between gum disease and heart disease. It has been known
for some time that there was a link, but it has been unclear until
now what causes it.
Scientists from the University of Bristol and the Royal College of
Surgeons in Ireland, now believe that bacteria, most likely the
Streptococcus bacteria which lives in the mouth, enters
the bloodstream via sore gums and deposits a clot-forming protein,
which increases the risk of heart attacks.
Speaking at the Society for General Microbiology’s autumn meeting
in Nottingham, Professor Howard Jenkinson who led the research,
explained that once the Streptococcus bacteria is in the
bloodstream, it can use a protein on their surface, called PadA as
a weapon to force platelets in the blood to bind together and form
clots. “When the platelets clump together they completely encase
the bacteria. This provides a protective cover not only from the
immune system, but also from antibiotics that might be used to
treat infection. Unfortunately, as well as helping out the
bacteria, platelet clumping can cause small blood clots, growth on
the heart valves, or inflammation of blood vessels that can block
the blood supply to the heart and brain."
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